Brain Function and Treatment Response for Internet Addiction Across the LifeSpan

1.0 CE Credit

Presented by:
David R. Rosenberg, MD
Chair, Dept. of Psychiatry & Behavioral Neurosciences 
Wayne State University 




Internet addiction or compulsive use of the internet has become an increasingly prevalent public health concern. The relationship between the clinical phenomenology and modes of brain dysfunction remains unclear. We describe an integrated series of clinical, neurobehavioral, and functional magnetic resonance imaging (fMRI) studies in patients with internet addiction. Based on findings from these studies, there appear to be at least four subtypes of internet addiction, including impulse control subtype, obsessive-compulsive subtype, inhibited (depressed-anxious) subtype, and combined impulse control and obsessive-compulsive subtype. fMRI studies reveal significantly decreased regional brain activation in response to targeted attention and working memory tasks in patients with internet addiction compared to healthy controls. After effective treatment, there appears to be normalization in brain circuitry; however, relapse in symptoms was associated with the reappearance of brain abnormalities. The need for transdisciplinary team interventions including psychiatry, neuropsychology, and innovative brain imaging techniques will be emphasized.

After the webinar, participants will be able to:
1. Describe the critical role of neuropsychology in the elucidation of potential brain mechanisms involved in the pathogenesis of internet addiction across the lifespan.
2. Identify key neuroimaging paradigms that are delineating regional brain abnormalities in internet addiction and their potential significance for enhanced diagnosis and treatment.
3. Discuss novel neurobehavioral and cognitive probes used during functional MRI studies and their role in further elucidating the pathogenesis of internet addiction.

Target Audience: Primary care providers, mental health providers, and direct patient care providers in other disciplines

Instructional Level: Introduction

Dr. David Rosenberg is Chair of the Department of Psychiatry & Behavioral Neurosciences at Wayne State where he also serves as the Director of the Translational Neurosciences Institute and the Miriam Hamburger Endowed Chair of Child Psychiatry. His research has focused on imaging genetic studies of neuropsychiatric disorders and he has led several large NIH consortium grants as lead PI at the lead/coordinating site. He has published extensively and been the recipient of numerous honors and awards including receiving first prize in the neuropsychoparmacology competition at the International Congress of Neuropsychopharmacology, the A.E. Bennett Award from the Society of Biological Psychiatry and the Psychiatric Times Teacher of the Year. He also published the first textbook on pediatric Psychopharmacology now in its third edition. He is frequently sought out by the national media and his research has been featured several times on the NBC Today Show, ABC 20/20, Good Morning America, ABC World News Tonight, CNN, PBS and NPR.

 
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Characterizing Neurocognitive Heterogeneity in Bipolar Disorder: Clinical Correlates and Inflammation-based Biomarkers

1.25 CE Credits

Presented by:
Dr. Katherine E. Burdick
Associate Professor of Psychology in Psychiatry
Harvard Medical School






Many patients with bipolar disorder (BD) suffer from persistent cognitive impairments, even during periods of effective remission, which contribute directly to functional disability. At the group level, the severity of these deficits is ¾ to 1 full standard deviation below average; however, substantial cognitive heterogeneity exists. Convergent data suggest that a cumulative burden of disease (e.g., recurrent mood episodes and other comorbid features) triggers a pro-inflammatory cascade, which drives the brain changes associated with cognitive and functional decline.  

After the webinar, participants will be able to:
        1. Characterize the cognitive profile common to bipolar disorder and compare it with that seen in schizophrenia.
        2. Identify the clinical correlates and biomarkers of cognitive impairment in bipolar patients.
        3. Describe the cognitive trajectory in bipolar disorder including both neurodevelopmental and neurodegenerative processes.

Target Audience: Psychologists, Neuropsychologists, Researchers or Clinicians treating patients with psychiatric diseases or symptoms; graduate students, other psychology trainees.

Instructional Level: Intermediate

Dr. Katherine E. Burdick is an Associate Professor of Psychology in Psychiatry at Harvard Medical School. She is the Director of the Mood and Psychosis Research Program and the Associate Vice Chair for Research in Psychiatry at Brigham and Women’s Hospital in Boston, MA. She has expertise in clinical and neurocognitive assessment across a range of patients with serious mental illness, including schizophrenia and bipolar disorder. 

Dr. Burdick obtained her Ph.D. in Clinical Neuropsychology from the City University of New York-The Graduate Center and completed her clinical internship and her postdoctoral fellowship at Yale University School of Medicine. She is a licensed clinical psychologist in the state of NY.

Dr. Burdick has a strong track record of both federal and foundation funding, with a primary research focus on identifying persistent cognitive deficits in major psychiatric disorders, understanding their etiologies, and directly targeting them with treatment. She has collaborated on a wide range of projects including neuroimaging, genetics, and treatment trials in patients with bipolar disorder, schizophrenia, and major depression and has authored more than 130 peer-reviewed publications in this area.

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Moving Towards Bright Futures: Maintaining Cognitive Health and Well-Being

3 CE Credits

Presented by:
Eduardo Esteban Bustamante, Ph.D., FACSM
Assistant Professor, Department of Kinesiology and Nutrition
Director, Healthy Kids Lab 
College of Applied Health Sciences
University of Illinois Chicago (UIC)




Lauren Strober, Ph.D.
Assistant Director, Cognitive Health and Well-being
The Center for Neuropsychology & Neuroscience Research 
Kessler Foundation
Research Associate Professor, Department of Physical Medicine & Rehabilitation
Rutgers, State University of New Jersey – New Jersey Medical School



Michelle Chen, Ph.D. 
Core Faculty Member, Institute for Health, Health Care Policy and Aging Research
Instructor, Department of Neurology, Robert Wood Johnson Medical School, Rutgers University






Brain health science has exploded in the last 15 years; however, many practitioners only have a general sense of related findings and clinical applications. All neuropsychologists and allied professionals, regardless of setting or clinical populations with whom they work, can benefit from updated knowledge related to the importance of protective and modifiable lifestyle factors (e.g., exercise, sleep, nutrition, intellectual activity, social engagement, stress management) on brain and cognitive health. This knowledge, in turn, can help clarify effective, evidence-based, brain-health recommendations for use in clinical practice from both a preventative and treatment perspective. This 3-hour virtual workshop is designed to inform the audience of recent advancements in brain health, with a focus on protective and modifiable lifestyle factors that promote well-being throughout the lifespan. Strategies for discussing brain and cognitive health recommendations with patients will also be emphasized. 

After the webinar, participants will be able to:
        1. Describe the role of health behaviors on youth neurocognitive development. 
        2. List the modifiable factors (i.e., person-specific and/or secondary factors) that have the greatest impact on brain health throughout the lifespan. 
        3. Describe the ways in which women and men are differentially impacted by some risk and protective factors in aging. 
        4. Develop and design strategies for educating patients about brain health

Target Audience: Health care providers are the primary audience, including neuropsychologists, clinical psychologists, social workers, other allied health professionals, physicians (including both pediatricians and geriatricians), nurses, and others with an interest in brain health and well-being.

Instructional Level: Intermediate

Eduardo Esteban Bustamante, Ph.D., FACSM is an Assistant Professor of Kinesiology and Nutrition and Director of the Healthy Kids Lab at University of Illinois Chicago (UIC). He holds a Ph.D. in Kinesiology, Nutrition, and Rehabilitation from UIC and completed a postdoctoral research fellowship at Medical College of Georgia. Dr. Bustamante studies relationships between health behaviors and mental health among children and families in underserved communities. This includes understanding the determinants of health behaviors, the generation of scalable community-engaged lifestyle interventions, and investigation of the neurocognitive and mental health consequences of health behaviors. His work has been funded by the National Institute of Mental Health, the National Institute of Minority Health and Health Disparities, the UIC Center for Health Equity Research, and the Chicago Partnership for Health Promotion.

Dr. Lauren Strober is the Assistant Director of Cognitive Health and Well-being in the Center for Neuropsychology & Neuroscience Research (CNNR) at Kessler Foundation and a Research Associate Professor in Physical Medicine & Rehabilitation at Rutgers, State University of New Jersey – New Jersey Medical School. Dr. Strober’s research focuses on issues pertaining to psychological well-being and quality of life (QOL) for those living with multiple sclerosis (MS). More specifically, Dr. Strober examines:  (1) the phenomenological experience of secondary factors associated with MS and other neurological conditions (e.g., depression, fatigue, sleep disturbance, personality changes); (2) the influence of secondary factors on cognitive functioning, psychological well-being, and quality of life; (3) identification of person-specific factors (e.g., self-efficacy, personality) that are accountable for various outcomes (e.g., unemployment) following illness or injury; and (4) development of clinical interventions aimed at ameliorating the disease and person-specific factors found to account for detriments in health, functioning, and well-being for those with MS. She has been funded by the Epilepsy Foundation, NIH, NMSS, NIDILRR, Sanofi Genzyme, Biogen Idec, and Patterson Trust and has secured over $2 million dollars in external funding as Principal Investigator for her research in these areas.

Dr. Michelle Chen is a neuropsychologist with a Ph.D. in Clinical Psychology from Yeshiva University. She completed her clinical internship at the VA Maryland Health Care System and postdoctoral research training at Kessler Foundation. She is currently a core faculty member of the Institute for Health, Health Care Policy and Aging Research, and Instructor in the Department of Neurology at Robert Wood Johnson Medical School, Rutgers University. Her current research programs focus on modifiable risk factors for cognitive aging and remote symptom monitoring using digital technologies, with the long-term goals of developing and validating digital lifestyle interventions aimed at improving cognition in neurologic populations. Dr. Chen is the recipient of a K23 Mentored Career Development Award funded by the National Institutes of Health (NIH), studying the longitudinal impact of health and lifestyle risk factors for cognitive decline among persons with MS.

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